LIL-HM4B5B-100μg / 询价
LIL-HM4B5B-500μg / 询价
LIL-HM4B5B-500μgx2 / 询价
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Biotinylated Human LILRB5/CD85c/LIR-8 Protein
Recombinant Biotinylated Human LILRB5/CD85c/LIR-8 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Arg18-His456.[Accession | O75023-1]
The protein has a predicted MW of 49.9 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
Less than 1EU per μg by the LAL method.
> 95% as determined by Tris-Bis PAGE
> 95% as determined by HPLC
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3-6 months after reconstitution.
2-8°C for 2-7 days after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human LILRB5 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human LILRB5 is greater than 95% as determined by SEC-HPLC.
LILRB5, also known as CD85c andLIR-8, belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Ig-like domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 may act as receptor for class I MHC antigens.
CD85C ; LIR-8; LIR8
(1)Hogan L E , Jones D C , Allen R L. Expression of the innate immune receptor LILRB5 on monocytes is associated with mycobacteria exposure[J]. Scientific Reports, 2016, 6(1):21780.
