BTN-HM1A1B-100μg / 询价
BTN-HM1A1B-500μg / 询价
BTN-HM1A1B-500μgx2 / 询价
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Biotinylated Human BTN3A1/CD277 Protein (Primary Amine Labeling)
Recombinant Biotinylated Human BTN3A1/CD277 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln30-Gly254 [Accession | O00481-1].
The protein has a predicted MW of 25.3 kDa. Due to glycosylation, the protein migrates to 28-32 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
Less than 1EU per μg by the LAL method.
Supplied as 0.22μm filtered solution in PBS, 200mM Arginine (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human BTN3A1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Immobilized Anti-BTN3A1 Antibody, hFc Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human BTN3A1, His Tag with the EC50 of 9.4ng/ml determined by ELISA.
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A1 controls activation of human Vγ9/Vδ2 T cells by direct or indirect presentation of self and nonself phosphoantigens (pAg).
CD277; BTN3A1; BTF5; BT3.1; BTN3.1
(1) Rhodes DA, Chen HC, Price AJ, Keeble AH, Davey MS, James LC, Eberl M, Trowsdale J. Activation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin. J Immunol. 2015 Mar 1;194(5):2390-8. doi: 10.4049/jimmunol.1401064. Epub 2015 Jan 30. PMID: 25637025; PMCID: PMC4337483. Copy
