CCL-HE120 | 价格

CCL-HE120-100μg / 询价

CCL-HE120-500μg / 询价

CCL-HE120-500μgx2 / 询价

Human CCL20 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human CCL20 Protein is expressed from E.coli with His tag at the N-Terminus.
It contains Ala27-Met96 [Accession | P78556-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 9.3 kDa. The protein migrates to 12-14 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22μm filtered solution in PBS (pH 7.4).

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human CCL20 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

背景(Background)

Recent evidence suggests that CC chemokine ligand 20 (CCL20) is upregulated after subarachnoid hemorrhage (SAH). CCL20 is upregulated in an SAH mouse model and in cultured primary microglia and neurons. CCL20-neutralizing antibody alleviated SAH-induced neurological deficits, decreased brain water content and neuronal apoptosis, and repressed microglial activation.

分子别名(Synonyms)

C-C motif chemokine 20; MIP-3-alpha; LARC; MIP3A; SCYA20; CKb4; Exodus; MIP-3a; ST38; exodus-1; MIP3 alpha

文献(References)

(1)Liao LS, Zhang MW, Gu YJ, Sun XC. Targeting CCL20 inhibits subarachnoid hemorrhage-related neuroinflammation in mice. Aging (Albany NY). 2020 Jun 21;12(14):14849-14862. doi: 10.18632/aging.103548. Epub 2020 Jun 21. PMID: 32575072; PMCID: PMC7425437.