CD7-MM201 | 价格

CD7-MM201-100μg / 询价

CD7-MM201-500μg / 询价

CD7-MM201-500μgx2 / 询价

Mouse CD7 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Mouse CD7 Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Gln24-Pro150 [Accession | P50283].

分子量大小(Molecular Weight)

The protein has a predicted MW of 15.3 kDa. Due to glycosylation, the protein migrates to 25-28 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Mouse CD7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SPR Data

Human SECTM1, hFc Tag captured on CM5 Chip via Protein A can bind Mouse CD7, His Tag with an affinity constant of 4.46 μM as determined in SPR assay (Biacore T200) (QC Tets).

背景(Background)

CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B progenitor cells. Among CD8 T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells.

分子别名(Synonyms)

CD7 molecule; CD7; LEU-9; Tp40; TP41; GP40

文献(References)

(1)Gomes-Silva D , Srinivasan M , Sharma S , et al. CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies[J]. Blood, 2017:blood-2017-01-761320.