CDD-HM101-100μg / 询价
CDD-HM101-500μg / 询价
CDD-HM101-500μgx2 / 询价
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Human CD3D/CD3 delta Protein
Recombinant Human CD3D/CD3 delta Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Phe22-Ala105.[Accession | P04234-1]
The protein has a predicted MW of 10.4 kDa. Due to glycosylation, the protein migrates to 15 kDa based on Tris-Bis PAGE result.
Less than 1EU per μg by the LAL method.
> 95% as determined by Tris-Bis PAGE
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3-6 months after reconstitution.
2-8°C for 2-7 days after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human CD3 delta on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CD3 delta is greater than 95% as determined by SEC-HPLC.
T-cell surface glycoprotein CD3 delta chain, also known as CD3D, is a single-pass type I membrane protein.In immunology, the CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cells) and also T helper cells (CD4 naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.
CD3d; CD3D; CD3-DELTA; T3D; CD3 delta; T3DOKT3; CD3-DELTA; IMD19
(1)Penaranda C , Tang Q , Bluestone J A. Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells[J]. The Journal of Immunology, 2011, 187(4):2015-2022.
