EDA-HM0P111-100μg / 询价
EDA-HM0P111-100μg x 5 / 询价
EDA-HM0P111-100μg x 10 / 询价
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Human EDNRA Protein-VLP
Recombinant Human EDNRA Protein-VLP is expressed from HEK293.It contains Met1-Asn427 [Accession | P25101-1].
The target protein has a predicted MW of 76.3 kDa.
Less than 1EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS, 150mM L-Arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human EDNRA VLP at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-EDNRA Antibody, hFc Tag with the EC50 of 57.0ng/ml determined by ELISA (QC Test).
The endothelin-A receptor (Ednra) is involved in several physiological, pathological, and developmental pathways. Known for its function in vasoconstriction after being activated by endothelin-1, Ednra also controls cephalic neural crest cell development and appears to play a role in several pathologies, including cancer and periodontitis.
EDNRA; ET-A; ETA-R; hET-AR; ETA; ETRA
Zhang Y, Knutsen GR, Brown MD, Ruest LB. Control of endothelin-a receptor expression by progesterone is enhanced by synergy with Gata2. Mol Endocrinol. 2013 Jun;27(6):892-908. doi: 10.1210/me.2012-1334. Epub 2013 Apr 16. PMID: 23592430; PMCID: PMC3656236.
