HVE-HM111-100μg / 询价
HVE-HM111-500μg / 询价
HVE-HM111-500μgx2 / 询价
Human HVEM/TNFRSF14 Protein
Recombinant Human HVEM/TNFRSF14 Protein is expressed from HEK293 with His tag at the C-Terminus It contains Leu39-Val202 [Accession | Q92956-1].
The protein has a predicted MW of 18.5 kDa. Due to glycosylation, the protein migrates to 32-48 kDa based on Bis-Tris PAGE result.
>95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human HVEM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human HVEM is greater than 95% as determined by SEC-HPLC.
Immobilized Human HVEM, His Tag at 2 μg/ml (100 μl/Well) on the plate. Dose response curve for Human CD160, hFc Tag with the EC50 of 0.17 μg/ml determined by ELISA (QC Test).
Immobilized Human HVEM, His Tag at 2 μg/ml (100 μl/Well) on the plate. Dose response curve for Human BTLA, hFc Tag with the EC50 of 7.2 ng/ml determined by ELISA.
Immobilized Human HVEM, His Tag at 1 μg/ml (100 μl/Well) on the plate. Dose response curve for Human LIGHT, hFc Tag with the EC50 of 4.9 ng/ml determined by ELISA.
Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily. Two TNF superfamily ligands lymphotoxin α (TNF-β) and LIGHT (TNFSF14) are identified as cellular ligands for HVEM and initiate the positive signaling.
CD270; CD40-like protein; HVEM; LIGHTR; ATAR; TNFRSF14; TR2
(1) Granger S W, Rickert S. LIGHT-HVEM signaling and the regulation of T cell-mediated immunity[J]. Cytokine Growth Factor Rev, 2003, 14(3):289-296.
