ISF-MM111 | 价格

ISF-MM111-100μg / 询价

ISF-MM111-500μg / 询价

ISF-MM111-500μgx2 / 询价

Mouse VSIG3/IGSF11 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Mouse VSIG3/IGSF11 Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Leu23-Val240 [Accession | P0C673].

分子量大小(Molecular Weight)

The protein has a predicted MW of 24.22 kDa. Due to glycosylation, the protein migrates to 38-42 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Mouse VSIG3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Mouse VSIG3 is greater than 95% as determined by SEC-HPLC.

背景(Background)

Immunoglobulin superfamily member 11 (IgSF11), a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors (AMPARs).

分子别名(Synonyms)

IgSF11; Bt-IGSF; Bt IGSF; BtIGSF; VSIG3; CXADRL1; CT119

文献(References)

Jang S, Oh D, Lee Y, Hosy E, Shin H, van Riesen C, Whitcomb D, Warburton JM, Jo J, Kim D, Kim SG, Um SM, Kwon SK, Kim MH, Roh JD, Woo J, Jun H, Lee D, Mah W, Kim H, Kaang BK, Cho K, Rhee JS, Choquet D, Kim E. Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity. Nat Neurosci. 2016 Jan;19(1):84-93. doi: 10.1038/nn.4176. Epub 2015 Nov 23. PMID: 26595655; PMCID: PMC5010778.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.