KGF-HE001-100μg / 询价
KGF-HE001-500μg / 询价
KGF-HE001-500μgx2 / 询价
Human FGF-7/KGF Protein
Recombinant Human FGF-7/KGF Protein is expressed from E.coli without tag.It contains Cys32-Thr194 [Accession | P21781-1].
The protein has a predicted MW of 18.88 kDa same as Bis-Tris PAGE result.
>95% as determined by Bis-Tris PAGE
Less than 0.1EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human FGF-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Immobilized Human FGF-7, No Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human FGFR2 beta (IIIb), hFc Tag with the EC50 of 0.36μg/ml determined by ELISA (QC Test).
The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demonstrate that the developing ureteric bud and mature collecting system of FGF-7-null kidneys is markedly smaller than wild type. FGF-7 levels modulate the extent of ureteric bud growth during development and the number of nephrons that eventually form in the kidney.
FGF-7; HBGF-7; KGF; FGF7
(1) Qiao J, Uzzo R, Obara-Ishihara T, Degenstein L, Fuchs E, Herzlinger D. FGF-7 modulates ureteric bud growth and nephron number in the developing kidney. Development. 1999 Feb;126(3):547-54. PMID: 9876183.
