KGF-HE001 | 价格

KGF-HE001-100μg / 询价

KGF-HE001-500μg / 询价

KGF-HE001-500μgx2 / 询价

Human FGF-7/KGF Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human FGF-7/KGF Protein is expressed from E.coli without tag.
It contains Cys32-Thr194 [Accession | P21781-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 18.88 kDa same as Bis-Tris PAGE result.

纯度(Purity)

>95% as determined by Bis-Tris PAGE

内毒素(Endotoxin)

Less than 0.1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human FGF-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

ELISA Data

Immobilized Human FGF-7, No Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human FGFR2 beta (IIIb), hFc Tag with the EC50 of 0.36μg/ml determined by ELISA (QC Test).

背景(Background)

The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demonstrate that the developing ureteric bud and mature collecting system of FGF-7-null kidneys is markedly smaller than wild type. FGF-7 levels modulate the extent of ureteric bud growth during development and the number of nephrons that eventually form in the kidney.

分子别名(Synonyms)

FGF-7; HBGF-7; KGF; FGF7

文献(References)

(1) Qiao J, Uzzo R, Obara-Ishihara T, Degenstein L, Fuchs E, Herzlinger D. FGF-7 modulates ureteric bud growth and nephron number in the developing kidney. Development. 1999 Feb;126(3):547-54. PMID: 9876183.