MCM-HM401B-100μg / 询价
MCM-HM401B-500μg / 询价
MCM-HM401B-500μgx2 / 询价
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Biotinylated Human MADCAM1 Protein
Recombinant Biotinylated Human MADCAM1 Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Gln19-Gln317 [Accession | Q13477-1].
The protein has a predicted MW of 34.31 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human MADCAM1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human MADCAM1 is greater than 95% as determined by SEC-HPLC.
Immobilized Biotinylated Human MADCAM1, His Tag at 0.5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-MADCAM1 Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA (QC Test).
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of our study was to determine whether selected single nucleotide polymorphisms (SNPs) of the MADCAM1 gene are associated with development of serious complications after aHSCT.
MAdCAM-1; MADCAM1; MACAM1
(1) Ambruzova Z, Mrazek F, Raida L, Stahelova A, Faber E, Indrak K, Petrek M. Possible impact of MADCAM1 gene single nucleotide polymorphisms to the outcome of allogeneic hematopoietic stem cell transplantation. Hum Immunol. 2009 Jun;70(6):457-60. doi: 10.1016/j.humimm.2009.03.008. Epub 2009 Mar 12. PMID: 19286444.
