MHC-HM426-100μg / 询价
MHC-HM426-500μg / 询价
MHC-HM426-500μgx2 / 询价
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Human HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer Protein
Recombinant Human CT83(HLA-A*01:01) Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*01:01), Ile21-Met119(B2M) and NTDNNLAVY peptide [Accession | Q5SUL5(HLA-A*01:01)&P61769(B2M)&NTDNNLAVY].
The protein has a predicted MW of 50.30 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer is greater than 95% as determined by SEC-HPLC.
Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
CT83; HLA class I; MHC class I; HLA-A; HLA-A*0101; MHC; MHC HLA-A alpha
Ye Z, Liang Y, Ma Y, Lin B, Cao L, Wang B, Zhang Z, Yu H, Li J, Huang M, Zhou K, Zhang Q, Liu X, Zeng J. Targeted photodynamic therapy of cancer using a novel gallium (III) tris (ethoxycarbonyl) corrole conjugated-mAb directed against cancer/testis antigens 83. Cancer Med. 2018 Jun 1;7(7):3057–65. doi: 10.1002/cam4.1601. Epub ahead of print. PMID: 29856138; PMCID: PMC6051178.
