OX4-HM240B-100μg / 询价
OX4-HM240B-500μg / 询价
OX4-HM240B-500μgx2 / 询价
Biotinylated Human OX40/TNFRSF4/CD134 Protein (Primary Amine Labeling)
Recombinant Biotinylated Human OX40/TNFRSF4/CD134 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu29-Ala216 [Accession | P43489].
The protein has a predicted MW of 46.8 kDa. Due to glycosylation, the protein migrates to 72-75 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
Less than 1EU per μg by the LAL method.
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human OX40 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
CD134; OX40; OX40L receptor; TNFRSF4; ACT-135; Ly-70; OX40 homologue; TXGP1L; IMD16
(1)Al-Shamkhani A , Mallett S , Brown M H , et al. Affinity and Kinetics of the Interaction between Soluble Trimeric OX40 Ligand, a Member of the Tumor Necrosis Factor Superfamily, and Its Receptor OX40 on Activated T Cells[J]. Journal of Biological Chemistry, 1997, 272(8):5275-5282.
