TAC-HM213-100μg / 询价
TAC-HM213-500μg / 询价
TAC-HM213-500μgx2 / 询价
Human TACI/TNFRSF13B Protein
Recombinant Human TACI/TNFRSF13B Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser2-Thr166 [Accession | O14836-1].
The protein has a predicted MW of 45.3 kDa. Due to glycosylation, the protein migrates to 38-40 kDa and 50-55 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human TACI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TACI is greater than 95% as determined by SEC-HPLC.
Immobilized Human BAFF Trimer, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human TACI, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test).
Transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) is one of the receptors of B cell activating factor of the tumor necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL). TACI is a regulator in the immune responses. TACI inhibits B cell expansion and promotes the differentiation and survival of plasma cells.
CD267; TNFRSF13B; TACI; CVID; CVID2; IGAD2; RYZN; TACI
(1) Zhang Y, Li J, Zhang YM, Zhang XM, Tao J. Effect of TACI signaling on humoral immunity and autoimmune diseases. J Immunol Res. 2015;2015:247426. doi: 10.1155/2015/247426. Epub 2015 Mar 17. PMID: 25866827; PMCID: PMC4381970.
