CD2-CM124V-100μg / 询价
CD2-CM124V-500μg / 询价
CD2-CM124V-500μgx2 / 询价
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Cynomolgus CD24 Protein-VLP
Recombinant Cynomolgus CD24 Protein-VLP is expressed from HEK293.It contains Ser26-Gly57 [Accession | XP_015304503.1 ]
The target protein has a predicted MW of 3.8 kDa.
> 90% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20°C or lower for 12 months as supplied from date of receipt.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Cynomolgus CD24 VLP on Bis-Tris PAGE under reduced conditions. The purity is greater than 90%.
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers.
CD 24; CD24 molecule; CD24A; FLJ22950; FLJ43543; MGC75043
(1)Barkal AA, et al.CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy.Nature. 2019 Jul 31. doi: 10.1038/s41586-019-1456-0.D
(2)Sun F, Wang T, Jiang J, et al. Engineering a high-affinity humanized anti-CD24 antibody to target hepatocellular carcinoma by a novel CDR grafting design[J]. Oncotarget, 2017, 8(31):51238-51252.
