CD3-CM138 | 价格

CD3-CM138-100μg / 询价

CD3-CM138-500μg / 询价

CD3-CM138-500μgx2 / 询价

Cynomolgus CD38 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Cynomolgus CD38 Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Leu44-Ile301 [Accession | Q5VAN0].

分子量大小(Molecular Weight)

The protein has a predicted MW of 31 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Cynomolgus CD38 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Cynomolgus CD38 is greater than 95% as determined by SEC-HPLC.

背景(Background)

CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a transmembrane glycoprotein found on the surface of some immune cells including plasma cells, activated or immature T and B cells, monocytes, and natural killer cells. CD38 participates in cell adhesion, signal transduction and calcium signaling.

分子别名(Synonyms)

ADPRC 1; T10; CD38; ADP-ribosyl cyclase 1; cADPr hydrolase 1; CD38 molecule; EC 2.4.99.20; EC 3.2.2.6

文献(References)

(1)Alba MatasCéspedes, Vidalcrespo A , Rodriguez V , et al. Daratumumab, a Novel Human Anti-CD38 Monoclonal Antibody for the Treatment of Chronic Lymphocytic Leukemia and B-Cell Non–Hodgkin Lymphoma[J]. Blood, 2012.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.