GP1-HM130-100μg / 询价
GP1-HM130-500μg / 询价
GP1-HM130-500μgx2 / 询价
- 客服电话
- 技术支持
Human gp130/CD130/IL-6 R beta Protein
Recombinant Human gp130/CD130/IL-6 R beta Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu23-Glu619 [Accession | P40189-1].
The protein has a predicted MW of 68.94 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human gp130 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human gp130 is greater than 95% as determined by SEC-HPLC.
gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130.
gp130; CD130; IL-6 R beta; IL-6R-beta; IL-6RB; CDw130; IL6ST
Nakashima K, Taga T. gp130 and the IL-6 family of cytokines: signaling mechanisms and thrombopoietic activities. Semin Hematol. 1998 Jul;35(3):210-21. PMID: 9685167.
