ILR-CM1R1-100μg / 询价
ILR-CM1R1-500μg / 询价
ILR-CM1R1-500μgx2 / 询价
Cynomolgus IL-13Ra1 Protein
Recombinant Cynomolgus IL-13Ra1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala25-Thr341 [Accession | XP_005594500.1].
The protein has a predicted MW of 37.59 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Cynomolgus IL-13Ra1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus IL-13Ra1 is greater than 95% as determined by SEC-HPLC.
Cynomolgus IL-13Ra1, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-13, His Tag with an affinity constant of 21.16 nM as determined in SPR assay (Biacore T200).
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
IL-13 R alpha 1; IL13R; IL13RA; CT19; IL13RA1; NR4; CD213A1
(1)Suzuki A , Leland P , Joshi B H , et al. Targeting of IL-4 and IL-13 receptors for cancer therapy[J]. Cytokine, 2015, 75(1):S1043466615002124.
