ILR-HM1R2 | 价格

ILR-HM1R2-100μg / 询价

ILR-HM1R2-500μg / 询价

ILR-HM1R2-500μgx2 / 询价

Human IL-13Ra2 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human IL-13Ra2 Protein is expressed from HEK293 with His tag at the C-terminus.
It contains Asp27-Leu342 [Accession | Q14627].

分子量大小(Molecular Weight)

The protein has a predicted MW of 38.28 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human IL-13Ra2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Human IL-13Ra2 is greater than 95% as determined by SEC-HPLC.

ELISA Data

Immobilized Human IL-13, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human IL-13Ra2, His Tag with the EC50 of 8.6ng/ml determined by ELISA.

背景(Background)

Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.

分子别名(Synonyms)

CD213a2; IL-13 R alpha 2; IL13BP; IL13R; IL13RA2; IL-13R subunit alpha-2; IL-13Ra2

文献(References)

(1)Suzuki A , Leland P , Joshi B H , et al. Targeting of IL-4 and IL-13 receptors for cancer therapy[J]. Cytokine, 2015, 75(1):S1043466615002124.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.