ILR-HM4R2B | 价格

ILR-HM4R2B-100μg / 询价

ILR-HM4R2B-500μg / 询价

ILR-HM4R2B-500μgx2 / 询价

Biotinylated Human IL-13Ra2 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Biotinylated Human IL-13Ra2 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.
It contains Asp27-Leu342 [Accession | Q14627].

分子量大小(Molecular Weight)

The protein has a predicted MW of 40.09 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22 μm filtered solution in PBS (pH 7.4).

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Biotinylated Human IL-13Ra2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Biotinylated Human IL-13Ra2 is greater than 95% as determined by SEC-HPLC.

ELISA Data

Immobilized Human IL-13, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-13Ra2, His Tag with the EC50 of 15.5ng/ml determined by ELISA (QC Test).

背景(Background)

Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.

分子别名(Synonyms)

CD213a2; IL-13 R alpha 2; IL13BP; IL13R; IL13RA2; IL-13R subunit alpha-2; IL-13Ra2

文献(References)

(1)Suzuki A , Leland P , Joshi B H , et al. Targeting of IL-4 and IL-13 receptors for cancer therapy[J]. Cytokine, 2015, 75(1):S1043466615002124.