SLA-HM2MF-100μg / 询价
SLA-HM2MF-500μg / 询价
SLA-HM2MF-500μgx2 / 询价
Human CD48/SLAMF2 Protein
Recombinant Human CD48/SLAMF2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln27-Ser220 [Accession | P09326-1].
The protein has a predicted MW of 48.9 kDa. Due to glycosylation, the protein migrates to 62-72 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human CD48 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CD48 is greater than 95% as determined by SEC-HPLC.
Immobilized Human 2B4, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human CD48, hFc Tag with the EC50 of 0.34μg/ml determined by ELISA.
CD48, also known as BLAST-1, BCM-1, and SLAMF2, is a 65 kDa GPI-linked protein in the CD2 family of immunoglobulin superfamily molecules.CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors.
CD48 molecule; CD48; SLAMF2; BCM1; BLAST; BLAST1; BLAST1TCT.1; mCD48; MEM-102; TCT.1
(1)Velikovsky C A , Deng L , Chlewicki L K , et al. Structure of Natural Killer Receptor 2B4 Bound to CD48 Reveals Basis for Heterophilic Recognition in Signaling Lymphocyte Activation Molecule Family[J]. Immunity, 2007, 27(4):0-584.
