TRM-HM101-100μg / 询价
TRM-HM101-500μg / 询价
TRM-HM101-500μgx2 / 询价
Human TREM1 Protein
Recombinant Human TREM1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala21-Arg200 [Accession | NP_061113.1].
The protein has a predicted MW of 21.4 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Bis-Tris PAGE result.
>95% as determined by Bis-Tris PAGE
>95% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human TREM1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TREM1 is greater than 95% as determined by SEC-HPLC.
Human PGLYRP1, hFc Tag captured on CM5 Chip via Protein A can bind Human TREM1, His Tag with an affinity constant of 17.39 µM as determined in SPR assay (Biacore T200).
TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear.
CD354; TREM-1
(1) Replogle JM, Chan G, White CC, Raj T, Winn PA, Evans DA, Sperling RA, Chibnik LB, Bradshaw EM, Schneider JA, Bennett DA, De Jager PL. A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology. Ann Neurol. 2015 Mar;77(3):469-77. doi: 10.1002/ana.24337. PMID: 25545807; PMCID: PMC4461024.
